Rice, a staple food for half the world’s population, is deficient in micronutrients such as iron and zinc, which are crucial yet often lacking in the human diet. Our goal is to understand how rice plants absorb these minerals and why only a small fraction is transported to the grains. To achieve this, we propose two strategies: i) analyzing all species of the Oryza genus, which are wild relatives of rice; ii) utilizing a collection of mutagenized rice plants with sequenced genomes, enabling us to identify the mutations present in each lineage. We will analyze the grains of all these strains to identify those with the highest amounts of iron and zinc. In these plants, we will pinpoint the genes responsible for this increase, thereby understanding the nutrient transport mechanism to the grains. Our aim is to swiftly generate plants with grains enriched in iron and zinc, which could significantly impact human nutrition.