Originally from Italy, Sara Gemini Piperni graduated from a rigorous Italian high school curriculum that emphasized Latin, Greek, and art history. Now living in Brazil, she blends her Renaissance roots with the exuberant energy of Rio de Janeiro by meditating while cooking, pondering new ideas while hiking, and hosting research meetings over homemade carbonara and fresh bread. For her, science stems from asking the right questions, many of which are inspired during lively gatherings around good food.
Her research recreates the intricate interactions between tumors and the immune system in the lab. Her goal is to understand the body’s response to cancer treatments without relying on animal models. Piperni studied biopharmaceutical technology at the University of L’Aquila, earning a master’s degree in cellular and molecular biotechnology, and completed an internship at Sierra Nevada College in the United States. She also completed her Ph.D. at L’Aquila, which included an internship at Inmetro.
With her background in biomaterials, nanotechnology, and bone metabolism, she now directs Labεn, a state-of-the-art bioengineering and health innovation laboratory at the Federal University of Rio de Janeiro.
Understanding how the human immune system detects and combats cancer is crucial for developing more effective therapies. Our project involves creating a miniaturized laboratory platform where tumor and immune cells can interact in precise, controlled conditions, thus eliminating the need for animal testing. Using microfluidic technology to mimic blood flow and incorporating three-dimensional tumor models allows us to observe these cellular interactions closely. This approach aims to predict how individual patients might respond to specific treatments. Ultimately, our goal is to create accessible, personalized solutions for the SUS, moving toward more effective, ethical, and cost-efficient healthcare.
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