Why don’t some people’s brains age?
Science / Life Sciences
This research seeks to understand the mechanisms underlying this phenomenon. Lifespan and cognitive aging vary widely. Some older adults maintain sharp memories into advanced age, even in the presence of underlying brain lesions. Our goal is to investigate whether neuroinflammatory and vascular factors protect the brain, increase the risk of disease, or contribute to the prevention of degenerative conditions. Understanding brain resilience is essential for identifying new therapeutic targets, particularly since most drugs for memory loss or Alzheimer’s disease have not stopped disease progression. By pinpointing biological pathways that support healthy brain aging, we hope to promote better outcomes by reducing neuroinflammation and minimizing vascular burdens accumulated over the lifespan.
Amount invested
Institutions
- Universidade Federal do Rio Grande do Sul