Development of a predictive biosensor for Cytokine release syndrome

Chemistry, Life Sciences

Coordinators

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Rodrigo Ramos

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Daniel Grassechi

This project aims to address cytokine release syndrome (CRS) in patients treated with CAR-T cells, which are used in cancer immunotherapy. The project proposes using nanomaterial-based biosensors, such as graphene or metallic nanoparticles, to detect the presence of IL-6 early and predict the occurrence of CRS, allowing for early treatment of toxic reactions. This approach aims to reduce severe clinical events, hospitalization time, and drug costs, benefiting patients’ health and reducing expenses for the public health system (SUS).

Amount invested

Grant 2023: R$ 31.915,00