Mechanisms of Thromboinflammation in Viral Infections

Science / Life Sciences

Platelets are traditionally known for their role in blood clotting, but their involvement in the immune response has become increasingly apparent. The main objective of the project is to investigate how platelets participate in immune regulation during viral infections such as dengue and COVID-19. The main focus of the project is to investigate the interplay between platelets and lymphocytes, which are white blood cells of the immune system. Lymphocytes play multiple roles in the response to infectious agents, including producing antibodies, eliminating infected cells, and generating memory. The study is dedicated to investigating how platelets and lymphocytes communicate, and how the components of coagulation and the immune system work together to contribute to the elimination of viral reservoirs, antibody production, inflammation, and even immune memory.

Amount invested

2022 Grant: R$ 700,000.00

Open Calls

Science Call 5