Metabolic and DNA Checkpoints Modulating Aluminum Tolerance: A tale of resilience in plants

Science / Life Sciences

Soil acidity (pH≤ 5.5), a major obstacle to sustainable food production in developing countries, leads to the solubilization of aluminum cations (Al). This process damages the DNA structure and alters mitochondrial respiration in plant roots. Despite intensive efforts to understand the role of DNA repair and mitochondrial organic acids in creating Al-tolerant plants, isolated manipulations at the DNA and mitochondrial metabolism checkpoints have not yielded sufficient results. This proposal, therefore, seeks to comprehend how DNA repair mechanisms can be integrated with mitochondrial metabolism in plants exposed to Al. Unraveling these connections could reduce the reliance on correctives and fertilizers, promote sustainable agricultural practices, and pave the way for developing the next generation of Al-tolerant materials.

Amount invested

R$ 97,895.00
  • Topics
  • Aluminum cations
  • Food production
  • Mitochondrial metabolism