Rafael Victorio Carvalho Guido

Chemistry, Life Sciences

Pharmacist and biochemist Rafael Guido graduated from Universidade Estadual Paulista Júlio de Mesquita Filho. He continued his academic journey at the University of Marburg, Germany on a sandwich fellowship, and later earned a doctorate in applied physics from the University of São Paulo. Rafael’s scientific research is a significant contribution to the treatment of malaria. Currently, he serves as an associate professor at the São Carlos Physics Institute at the University of São Paulo. To stimulate his scientific thoughts, he maintains a running routine, often accompanied by podcasts. Outside of his professional life, Rafael enjoys spending time with his wife and two children, often ending the week around the barbecue with a good bottle of wine. His personal and professional life beautifully intertwines, creating a balance that fuels his passion for both family and scientific discovery.


Harnessing Structural Biology and Medicinal Chemistry for Malaria Drug Discovery: A strategic approach
Science / Life Sciences

Malaria is a grave global health concern, impacting over 216 million individuals and resulting in approximately 445,000 fatalities in 2016. The African region bore the brunt of these deaths, accounting for almost 90% of the total, with children under 5 and pregnant women being the most severely affected demographics. In response to this crisis, three Brazilian universities have joined forces to develop new compounds with promising activity and safety profiles for malaria treatment. Initial candidates, identified as potential molecules for optimization studies of pharmacodynamic and pharmacokinetic properties, are currently under investigation. This proposal is centered on discovering new drug candidates within Brazil, a significant stride toward combating this devastating disease.

Amount invested

R$ 100,000.00

Open Calls

Science Call 1
  • Topics
  • Drugs
  • Inhibitors
  • malaria
  • Pharmacodynamic properties