Prostate cancer is a global health concern affecting men worldwide. The behavior of cancer cells is influenced by the components of the tissue microenvironment they inhabit. Therefore, it is crucial to identify these constituents and comprehend their impact on tumor development. It is well-established that the peripheral nervous system plays a vital role in the growth and maintenance of the prostate. However, we are just starting to understand the function of nerve projections and their associated cells in the progression of prostate cancer. This project aims to delve into the role of the peripheral nervous system within the tumor microenvironment. The findings from this research could potentially pave the way for an innovative therapeutic approach to treating prostate cancer and other similar conditions.